Intelligent Medicine

Dr. Lindsey Berkson is a world-renowned expert on hormone replacement therapy. She shares her journey as a DES baby with multiple endocrine challenges, including reproductive cancers. Through exhaustive research she overcame her problems and enjoys high functioning at an age where many women are in steep decline. She discusses various forms of hormone replacement, why conventional ideas about menopause treatment are misguided, how supplements can enhance the safety and efficacy of hormone replacement, and the impact of dietary factors like soy. She has written extensively about the effects of hormone disruptors on women’s health. Check out her membership program, Everything Hormones, and her Substack, Agile Thinking.

Dr. Hoffman continues his conversation with Dr. Lindsey Berkson is a world-renowned expert on hormone replacement therapy.

Dr. Edward Walker, a scientist from the New Zealand Institute for Plant and Food Research, details the rigorous research process behind Calocurb, a natural product aimed at curbing appetite and fighting obesity. Dr. Walker explains how his team identified and formulated Amarasate, a compound derived from New Zealand hops, which mimics the appetite-suppressing effects of certain gastrointestinal hormones like GLP-1. The conversation also covers the evolution of the product, the scientific studies confirming its efficacy, and practical considerations for its use. They further delve into the challenges and potentials of using natural alternatives to pharmaceutical weight loss drugs.

Dr. Hoffman continues his conversation with Dr. Edward Walker, a scientist and lecturer with The New Zealand Institute for Plant and Food Research Limited, a New Zealand Crown Research Institute. He helped discover and develop Amarasate, the active ingredient in Calocurb.

“5:2” intermittent fasting outperforms diabetes drugs; Celebrity UK diet doc—proponent of intermittent fasting—tragically dies at 67 while hiking mountainous terrain on Greek holiday; Is L-serine good or bad for the brain? What’s the latest on the fish oil/cardiovascular disease controversy? Most Ozempic users quit before attaining weight loss goals; Benefits of Calocurb for weight loss. In turnaround, testosterone NOT found to hike cardio risk; Men with low T suffer early death; CBD chews combat anxiety, joint problems in pets.

“Ultra-Processed Foods DO NOT Cause Obesity” claims latest study from top U.S. diet policy makers; Florida Congresswoman takes aim at high-fructose corn syrup, food dyes in proposed bill; What’s the best natural sunscreen? Why is there DPA in fish oil—and is it beneficial? A caller’s doctor poo-poos vitamin D’s benefits for immunity; Natural support for GERD; Alzheimer’s slowed by lifestyle intervention in first-of-its-kind trial; Campaigns against misinformation backfire—by making people distrust legitimate information; Pentagon funds $450 million experimental project to deliver lab-grown meat to troops to “lower carbon footprint”.

The Connection Between Community Mobility, Exercise, and Cognitive Health. Nutritionist Leyla Muedin weighs in on the impact of community, mobility and exercise on cognitive function and overall health. She reviews recent studies, including one from the Journal of the American Geriatric Society, highlighting how greater community and mobility can be associated with better cognitive function, and another study from the journal Aging Cell that demonstrates exercise’s beneficial effects on brain health at the cellular level in mice. Additionally, Leyla discusses the harmful effects of air pollution on brain health and the importance of a holistic approach, emphasizing both physical activity and healthy lifestyle choices to mitigate cognitive decline and improve well-being.

Mask confusion is reigning in New York; A case of high dose curcumin in the treatment of kidney disease and psoriasis; Nystatin therapy for the treatment of candida.

What kind of sweetener can I use in my daily coffee and tea?; I have an asymptomatic urinary tract infection. Must I take an antibiotic?; I've been on a low carb diet for 16 months. When will my diabetes go away?; I recently had hip surgery and want to take care of my joints. What supplements do you recommend?; Do you have a recommendation for my pet's joint health too?; How can I treat or manage emphysema?

Alex Martinez, CEO and co-founder of Intrinsic Medicine reveals the potential of utilizing human milk biology, specifically the microbiome and human milk oligosaccharides (HMOs), to address various medical challenges such as Parkinson's disease, autism spectrum disorder, irritable bowel syndrome, Alzheimer's disease, and inflammatory bowel disease. Alex shares his journey from being an attorney to starting a therapeutics company focused on the innovative use of human milk's properties. The conversation also delves into the science behind HMOs, their evolutionary significance, and their potential impact on the microbiome and immune system. This episode provides insights into the cutting-edge research and the promising future of natural, less toxic, and cost-effective therapeutic solutions.

Dr. Hoffman continues his conversation with Alex Martinez, the CEO and co-founder of Intrinsic Medicine, a therapeutics company leveraging human milk biology to transform Gut-Immune-Brain Axis (GIBA) disorders such as Parkinson’s, Autism Spectrum Disorder, IBS, Alzheimer’s, and IBD, among other illnesses.

Although cardiovascular disease is usually thought of as a man’s disease, almost as many women die each year of heart problems. Jane Jansen, a naturopathic practitioner from the Tree of Life Wellness Center in Massachusetts brings a unique perspective with her extensive background in cardiovascular labs and non-invasive cardiology. She sheds light on the gender disparities in cardiovascular research, the critical periods for women's heart health, especially during perimenopause and menopause, and the evolving understanding of hormone replacement therapy. The episode highlights the importance of early diagnosis, lifestyle changes such as diet and exercise, and the benefits of specific supplements like aged garlic extract. Jansen addresses the underestimation of women's cardiovascular risks compared to breast cancer and offer practical advice on managing stress and improving sleep quality. This comprehensive conversation aims to break stereotypes and provide actionable insights for better heart health among wom

Dr. Hoffman continues his conversation with Naturopathic Practitioner, Jane Jansen of the Tree of Life Wellness Center in Massachusetts.

As weight-loss meds surge in popularity, BigPharma builds pipeline of even more potent, pricey drugs—questions arise as to their sustainability, cost-effectiveness; 93 million Americans may be candidates for them, at an annual price tag of $600 billion; Tufts nutrition chief calls for 12-18 month limits on their use, conditioning their prescription on mandatory behavior modification for weight loss maintenance; German man opts for 217 Covid shots—researchers claim he’s still “fine”; Alpha lipoic acid for diabetic neuropathy; Does Motrin affect the liver? Consumer alert over “free” urinary catheter scams.

NYU doctor dies of anaphylactic shock after deadly food allergens not disclosed at Disney eatery; Pharmaceutical company fined $264 million for lifesaving Epi-Pen price-gouging; Nasal spray alternative to injectable epinephrine canceled over efficacy concerns; How microbiome imbalances predict food allergy susceptibility; Alternatives to expensive creams for bothersome skin rashes; Is krill oil compatible with blood thinners like Eloquis? Continuous glucose monitors cleared for over-the-counter sale without prescription; Hawthorne for congestive heart failure; Can high-dose vitamin D forestall juvenile onset diabetes? Microplastics and heart disease; FDA issues “qualified health claim” for yogurt as hedge against Type 2 diabetes.

Nutritionist Leyla Muedin explores the often overlooked topic of natural toxins in food. Drawing insights from the Integrative Medicine Journal, she discusses how plants protect themselves with chemical compounds that can pose health risks. She also delves into survey results from the German Federal Institute for Risk Assessment, revealing public awareness and concerns about these natural toxins compared to synthetic contaminants. The episode highlights the ongoing debate about the safety of consuming certain plant foods and the popularity of diets like the carnivore movement, which seek to avoid these natural plant compounds.

Can you please discuss the xylitol and cardiovascular risk study? Do I have to stop using xylitol spray, mouthwash and gum now? What about DGL?; I've been diagnosed with Atrial fibrillation. What do you think of Pulsed Field Ablation?; I have Hypertrophic Obstructive Cardiomyopathy. What would you recommend?; I'm 5' 2" and 185 lbs. Would I benefit from Calocurb?

What do you think of IV drip lounges? When would I use them? Do I need a doctor's prescription?; What supplements can I take to lower HS-CRP?; Is appetite physical or mental? It seems a lot of times I'm not hungry but I can't control my eating; How do you know if your GERD is from too much or too little stomach acid?

Dr. Alan Gaby comments on bias against nutritional supplements. He recently penned an op-ed entitled “They’re telling us that nutritional supplements are a waste of money”. He is the author of the textbook “Nutritional Medicine” which contains thousands of references to studies substantiating the benefits of supplements. Is there collusion between the pharmaceutical industry, government regulators, politicians, and compliant media to rein in the supplement industry? Why has the press uncritically focussed on the alleged harms of supplements? What’s wrong with studies claiming lack of efficacy of multivitamins, fish oil, and vitamin D? Dr. Gaby takes an even-handed approach, citing instances of over-arching claims about nutrients; he urges “humility” and scientific rigor in nutrition science, and decries the missed opportunity for study of the promising roles of diet, lifestyle, and nutraceuticals afforded by our quest for measures to control the pandemic.

Dr. Hoffman continues his conversation with Dr. Alan Gaby, author of the textbook “Nutritional Medicine."