Scott Cole Show

To kick off their 2022 NFL regular season, Josh Allen's Buffalo Bills take a trip across the country to take on the Los Angeles Rams. The Rams, fresh off a Super Bowl victory in September, start their quest to repeat against a team billed as a favorite to reach the big game this season. Matthew Stafford and Cooper Kupp lead a Rams offense supported by Aaron Donald and Jalen Ramsey on defense. Meanwhile, Allen and star receiver Stefon Diggs look to take the Bills to the next level, beginning with Thursday night's 8:20 p.m. ET kickoff at SoFi Stadium.