Agile Rabbit

We think about viruses as harmful to us, but research by our speaker Martha Clokie shows that some can improve our health. These tiny viruses known as ‘phages’ do this by invading bacteria, multiplying, and bursting out, eventually destroying their host. When these are bacteria that attack our bodies, this could be beneficial—our enemy’s enemy is our friend. Antibiotic resistance is one of the biggest threats to global health. As a result, a growing number of infections—such as pneumonia, sepsis and diarrhoea—are harder to treat. Professor Martha Clokie is leading the fight against antibiotic resistant bacterial infections with this vital research. In particular, her work shows the potential for the use of phages against superbugs such as Clostridium difficile, Salmonella, and Borrelia (the causative agent of Lyme disease). In May 2019, headlines around the world told the story of the successful phage treatment of Isabelle Carnell-Holdaway, a sufferer of cystic fibrosis who contracted tuberculosis, who