Future Science Group

TalkingTechniques with Mark Behlke: solving the off-target effects of CRISPR/Cas9

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Synopsis

We spoke to Mark Behlke, the chief scientific officer of Integrated DNA Technologies (IA, USA), about the current limitations of CRISPR/Cas9 techniques and the potential of the novel HiFI Cas9 enzyme to resolve these limitations, as shown in a sickle cell disease-causing mutation.